Naveen Kumar Reddy Yaragudi, Scientist, Janssen Drug Product Development and Devices, and Lipika Chablani, Associate Professor, Wegmans School of Pharmacy, St. John Fisher University
Historically, vaccination has proven to be an established prophylactic strategy against infectious diseases and has served as a healthcare tool to manage global pandemics. From smallpox to COVID-19, prophylactic vaccines have effectively curbed epidemics/pandemics. Edward Jenner's variolation from 1798 was the first vaccination record to ever be published. He inoculated cowpox viral pustule wet matter from infected humans to healthy individuals to prevent smallpox infections [1]. Louis Pasteur developed the first Pasteurella Multocida live attenuated vaccine for chicken cholera nearly eight decades later. Since then, vaccines have been developed utilizing whole cells, inactivated organisms, bacterial toxins, polysaccharides, and conjugated and genetically engineered vaccines.