Cover Stories

New functionality for small molecule therapeutics can advance drug development. By John Morrison, Ph.D., Bristol-Myers Squibb, and Steven Louie, Amgen The pharmaceutical industry continues to evolve, developing strategies to take advantage of novel ...

With products ranging in scope and complexity, implementing even a streamline regulatory framework may be challenging. By Stefan Leiner, Ph.D., and Christoph Kreher, Ph.D., Boehringer Ingelheim Pharma GmbH & Co. KG   In the European Union (E.U.), the ...

Global input on harmonizing bioanalytical method validation solidified scientists’ vision and outlined universal challenges with existing guidelines. By Faye Vazvaei, M.S., Roche Innovation Center New York; Lakshmi Amaravadi, Ph.D., Shire Plc; Lindsay ...

Microdialysis can reveal pharmacokinetics and physiological changes in tissue. By Benjamin Kuzma, Long Island University, and Nimita Dave, AbbVie Microdialysis is a powerful semi-invasive technique that enables continuous measurement of local drug, ...

Adopting twin-screw granulation can aid in the transition from batch to continuous processes for pharmaceuticals. By Nada Kittikunakorn, University of Texas at Austin; James DiNunzio, Ph.D., Merck & Co., Inc.; Charlie Martin, Leistritz Extrusion; Feng ...