Novel Approaches Targeting Brain Barriers for Effective Delivery of Therapeutics
April 29–May 1, 2019
Herndon, Va.
Cosponsored by
This workshop will focus on novel science, insights, tools, and approaches for targeting and bypassing the central nervous system (CNS) barriers to achieve drug delivery to the brain and spinal cord. Barriers to the CNS include the blood-brain barrier and the blood-cerebrospinal fluid barriers.
The goal is to both clarify the main issues for the field and discuss the most cutting-edge current and future strategies for CNS drug delivery. The workshop will cover the following topics:
- Physiology and regulation of CNS barriers
- Molecular mechanisms of brain permeability and targeting
- Novel CNS targeting strategies for crossing and bypassing the barriers
- Models and in vitro-in vivo correlations
Each day will begin with a plenary session featuring a keynote speaker: Rita Balice-Gordon, Ph.D., of Sanofi Genzyme Inc. will talk about Drug Delivery to the Brain: Integrating Neuroscience, Physiology, and Brain Barriers Science Considerations in the Development of New Therapies. Margareta Hammarlund-Udenaes, Ph.D., of Uppsala University will discuss Pharmacokinetic Concepts in CNS Drug Delivery and Distribution Modern and Emerging Views. Ryan Watts, Ph.D., of Denali Therapeutics will speak about Engineering Brain Delivery to Treat Neurodegenerative Disease.
Early Bird Registration ends April 9th!
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Get information about this and other workshop sponsorship opportunities from Katherine Wrona.
See the detailed agenda with speakers, and register.
AAPS Forum to Connect Predictive Modelers
May 6–7, 2019, Boston
Rarely do we cross outside of our area of expertise and engage with modelers in other pharma disciplines. There are many opportunities for education and collaboration that are missed because we are not talking enough with one another!
This workshop will bring together predictive modelers from academia, industry, and regulatory environments working in the pharmaceutical sciences to share modeling philosophies and best practices. Focal points will include technical methodologies and tools as well as strategic approaches for communication and influence. We will be introduced to some of the latest predictive modeling tools and technologies. The goal is to identify opportunities to work together to provide a more comprehensive and influential quantitative basis for making decisions.
Participants of this workshop will:
- compare and contrast tools, techniques, and language across predictive modeling disciplines in pharmaceutical sciences;
- discuss modeling philosophy and create best practices for predictive modeling;
- develop approaches for influencing decision makers through strategic communication of modeling results;
- discover state-of-the-art and emerging tools and technologies to motivate future development of predictive modeling in pharmaceutical sciences; and
- identify opportunities for collaboration, efficiency gain, and cross-discipline learning.
Speakers will address modeling in quantitative systems pharmacology, biopharmaceutics, bioinformatics, pharmacometrics, and QSAR models. Breakout sessions will give attendees the opportunity to compare and contrast modeling disciplines, identify the biggest challenges, and brainstorm solutions for those challenges. Fang Wu, Ph.D., of the Food and Drug Administration will discuss biopharmaceutics.
See the detailed agenda with speakers, and register.
2019 Land O’Lakes Conferences
Developed and conducted by the Division of Pharmacy Professional Development, School of Pharmacy, University of Wisconsin-Madison, and in partnership with AAPS.
20th Annual Bioanalytical Conference
July 15 – 19, 2019
Innovation in Bioanalytical Research for Translational Medicine: New Modalities, New Technologies, and Evolving Regulations
This conference is designed to advance topics related to bioanalysis such as xenobiotics, metabolites, biologics, and biomarkers. An optional short course on “Gene Therapy Fundamentals” is available. This year’s conference addresses new modalities, new technologies, and evolving regulations in bioanalysis: Gene Therapy, Multiomics Miniaturization, and Bioanalysis Regulation.
59th Annual Pharmaceutical Analysis Conference
August 12 – 15, 2019
Addressing Technical and Regulatory Challenges in Pharmaceutical Analysis
Learn about statistical techniques and their applications in the pharmaceutical industry at this conference, which will focus on navigating the technical and regulatory challenges. Industry leaders and regulators will present and answer the most common questions. Plenary sessions include the following:
- Current Challenges to Pharmaceutical Analysis
- Focus on Large Molecules
- New Technologies and Approaches for Increasing Laboratory Efficiency
- Global Regulatory Challenges to Pharmaceutical Analysis
22nd Annual Drug Metabolism and Applied Pharmacokinetics Conference
September 9 – 12, 2019
Found in Translation: Adaptive DMPK Strategies
Address drug safety evaluation and other topics related to drug metabolism and pharmacokinetics. There will be an optional short course on “Human Dose Projections.” This year we will discuss absorption, distribution, metabolism, and elimination in pharmacokinetics and pharmacodynamics. Plenary sessions include the following topics:
Endogenous Biomarkers
Target Mediated Drug Disposition
Microphysiological Systems
Disposition in New and Nontraditional Therapeutic Modalities