Nucleic Acid-Based Therapeutics and Organ-Specific Therapies

Prepare for the 2019 AAPS PharmSci 360 by reading innovative journal articles.

The 2019 AAPS PharmSci 360 conference, November 3–6 in San Antonio, features End-to-End topics that will run throughout track programming. Make the most of your PharmSci 360 experience by reading research in these hot topic areas before you delve into PharmSci 360 programming.

Biomolecular: Nucleic Acid-Based Therapeutics: Discovery, Development, and Delivery

The AAPS Journal

• Nanoparticle-Based Delivery of CRISPR/Cas9 Genome-Editing Therapeutics
• The Phenotypic Effects of Exosomes Secreted from Distinct Cellular Sources: a Comparative Study Based on miRNA Composition

The pathways of NP-mediated CRISPR/Cas9 delivery to the nucleus. doi: 10.1208/s12248-018-0267-9

AAPS PharmSciTech

• Nucleic Acid-Based Therapeutics for Pulmonary Diseases
• Optimization of Chitosan-α-casein Nanoparticles for Improved Gene Delivery: Characterization, Stability, and Transfection Efficiency

Pharmaceutical Research

• Nasal Administration of Cationic Nanoemulsions as Nucleic Acids Delivery Systems Aiming at Mucopolysaccharidosis Type I Gene Therapy
• High Pressure Nebulization (PIPAC) Versus Injection for the Intraperitoneal Administration of mRNA Complexes

Chemical: The Journey to Developing Tissue- and Organ-Specific Therapies

The AAPS Journal

• THEME: Recent Advances in Musculoskeletal Tissue Engineering

AAPS PharmSciTech

• THEME: Advances in Topical Delivery of Drugs
• THEME: Advances in Formulation and Device Technologies for Pulmonary Drug Delivery

AAPS Open

• Nano-formulations composed of cell membrane-specific cellular lipid extracts derived from target cells: physicochemical characterization and in vitro evaluation using cellular models of breast carcinoma

Pharmaceutical Research

• Theme: Ophthalmic Drug Discovery and Development

AAPS members can access full text for all of AAPS’ online journal articles by logging in and clicking through once on any cover. AAPS Open articles are all open access.